Martin J. Field



Portrait      
Address: Laboratoire de Dynamique Moléculaire
  Institut de Biologie Structurale - Jean-Pierre Ebel (CEA/CNRS/UJF)
  41 rue Jules Horowitz
  38027 Grenoble Cedex 1
  FRANCE
Telephone: (33)-4-38-78-95-94
Email:  mjfield@ibs.fr
Web:  www.ibs.fr


Current Position:  Group leader of the Laboratoire de Dynamique Moléculaire at the Institut de Biologie Structurale in Grenoble, France.
      
Research Interests:     The development and application of computational and theoretical tools for understanding processes of biological interest at the molecular level.
      
Algorithmic Projects:    
  • Hybrid quantum mechanical/molecular mechanical (QM/MM) potentials for studying reactions in solution and in enzymes.

  • Methods for determining the free-energy profiles and the rates of transition processes in complex systems.

  • Conformational search techniques.

Application Projects:    
  • Various enzymatic reaction mechanisms. Recent studies have concerned cAMP-dependent protein kinase, chorismate mutase, hypoxanthine-guanine-xanthine phosphoribosyltransferase, neuraminidase and the penicillin-binding proteins.

  • Conformational transitions and ligand-diffusion in proteins. Recent studies have concerned catalase and the H-protein.

  • Simulation of self-assembly and self-organization processes.

Contact mjfield@ibs.fr for further information about research, for possible graduate and postdoctoral positions in the group and for reprints.