[buster-discuss] rhofit ??
osmart at globalphasing.com
Wed Jun 29 19:08:46 CEST 2011
On Wed, 29 Jun 2011, Jonathan Grimes wrote:
> Dear Buster Developers,
> We have solved the structure of a viral polymerase bound
> to viral adaptor protein. We can see clear density for a peptide
> 10-15aa, so much smaller than the full length adaptor
> protein. We dont know if the rest of the adaptor protein is in crystal (and
> is disordered) or had been cleaved.
> We are also unclear of the peptide sequence at the moment (data to ~2.3A).
> Is ligand fitting Rhofit appropriate to use ?? Ive never used Rhofit but have
> only heard good stories.
We have never tried rhofit on something this big. It handles cyclodextran
but this sound like a case for normal coot type building?
| Dr Oliver Smart |
| Global Phasing Ltd., Cambridge UK |
| http://www.globalphasing.com/people/osmart/ |
More information about the buster-discuss